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A GABA antagonist would be likely to produce:


A) decreased anxiety and activity.
B) increased anxiety and activity.
C) respiratory depression.
D) visual hallucinations.

E) B) and C)
F) A) and C)

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Antipsychotic drugs are thought to exert their effects, at least in part, by blocking one type of:


A) glutamate receptor.
B) thought process.
C) dopamine receptor.
D) action potential.

E) B) and C)
F) None of the above

Correct Answer

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Diverse drugs of abuse may act through a common neurotransmitter system that releases:


A) endorphin.
B) serotonin.
C) dopamine.
D) GABA.

E) A) and B)
F) A) and C)

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A drug that is _____ is more readily absorbed from the stomach than one that is _____.


A) weakly basic; weakly acidic
B) weakly acidic; weakly basic
C) insoluble; soluble
D) digestible; indigestible

E) A) and B)
F) A) and C)

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The blood-brain barrier is established by:


A) neurons and astrocytes.
B) neurons and smooth muscle cells.
C) endothelial cells and neurons.
D) endothelial cells and astrocytes.

E) B) and C)
F) None of the above

Correct Answer

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The need to take increasing amounts of a drug in order to experience the same physical effect is called:


A) sensitization.
B) tolerance.
C) addiction.
D) dependence.

E) A) and B)
F) C) and D)

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The brain's capillary network is largely isolated from that of the body's general circulation by the:


A) peripheral nervous system.
B) meninges.
C) blood-brain barrier.
D) Circle of Willis.

E) B) and C)
F) A) and B)

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The organizational effect of gonadal hormones is exerted during:


A) early development.
B) adolescence.
C) adulthood.
D) learning.
Answer Key

E) C) and D)
F) A) and C)

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Nicotine acts primarily on _____ receptors.


A) dopamine
B) acetylcholine
C) GABA
D) histamine

E) A) and D)
F) All of the above

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B

Which of the following is NOT a stimulant?


A) LSD
B) caffeine
C) cocaine
D) amphetamine

E) B) and C)
F) A) and B)

Correct Answer

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Which of the following factors is more associated with the development of sensitization than with the development of tolerance for a particular drug?


A) fatigue during task performance
B) neuroplastic brain changes only at the drug's site of action
C) regular use
D) occasional use

E) None of the above
F) B) and D)

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The study of the effects of drugs on the function of the nervous system is:


A) psychopharmacology.
B) neuroendocrinology.
C) pharmacokinetics.
D) biopsychology.

E) B) and C)
F) A) and D)

Correct Answer

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According to the incentive - sensitization theory of drug addiction, wanting a drug may depend on _____ neurons, whereas liking a drug may depend on _____ neurons.


A) dopamine; glutamate
B) GABA; opioid
C) dopamine; opioid
D) opioid; dopamine

E) A) and D)
F) C) and D)

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Isbell et al. reported that research participants who drank alcohol steadily for 20 days showed _____ degrees of intoxication _____ blood alcohol levels due to _____.


A) increasing; but not; sensitization
B) increasing; and; sensitization
C) decreasing; and; tolerance
D) decreasing; but not; sensitization

E) B) and C)
F) A) and D)

Correct Answer

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Tetrahydrocannabinol (THC) is an agonist of which endogenous neurotransmitter?


A) GABA
B) glutamate
C) dopamine
D) anandamide

E) A) and D)
F) B) and C)

Correct Answer

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A typical function of homeostatic hormones is:


A) activating sexual behaviors.
B) dealing with stressful psychological events.
C) controlling blood-sugar levels.
D) instructing the body to develop as a male or female.

E) None of the above
F) B) and D)

Correct Answer

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C

Which of the following is NOT likely to interact at endorphin synapses?


A) morphine
B) heroin
C) naloxone
D) lithium carbonate

E) A) and B)
F) All of the above

Correct Answer

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Most psychoactive drugs affect the functioning of the:


A) synapse.
B) astrocytes.
C) dendrites.
D) axon hillock.

E) C) and D)
F) B) and D)

Correct Answer

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A drug that increases the effectiveness of neurotransmission is called a(n) :


A) antagonist.
B) agonist.
C) neuromodulator.
D) stimulant.

E) None of the above
F) A) and D)

Correct Answer

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B

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